• Sweden edition
 

Thinner girls at greater risk of cancer: study

Published: 16 Apr 2010 06:57 GMT+02:00
Updated: 16 Apr 2010 06:57 GMT+02:00

The surprising conclusion is made by Karolinska Institutet researchers who looked at data from 2,818 Swedish breast cancer patients and 3,111 healthy counterparts.

"Large body type at age seven years was associated with a decreased risk of post-menopausal breast cancer," said lead researcher Jingmei Li.

"It appears counterintuitive that a large body size during childhood can reduce breast cancer risk, because a large birth weight and a high adult BMI have been shown to elevate breast cancer," Li added.

"There remain unanswered questions on mechanisms driving this protective effect."

BMI means body mass index, a measure of fat.

A girl's BMI at the age of seven also dictates the risk of so-called oestrogen receptive negative tumours, where the outcome is often less favourable than other cancer types, said the study.

The paper is published online in an open-access, peer-reviewed journal, Breast Cancer Research.

Separately, in a paper published on Wednesday in the journal Nature, scientists drew a map of 20 genetic mutations behind a highly lethal, fast-spreading form of breast cancer.

So-called "triple negative" breast cancer disproportionately affects younger women and those who are African-American.

The gene profile came from a 44-year-old African-American woman who was killed within months after breast cancer spread to her brain.

The work adds to knowledge about fast-track breast cancer and throws up new drug targets for women diagnosed with "triple negative" tumours, said Elaine Mardis, co-director of the Genome Center at Washington University.

"We are getting an intimate look at the lethal spread of a breast cancer, which is now possible because we can sequence entire genomes quickly at a reasonable cost," said Mardis.

The first draft of human genetic code was published nearly a decade ago, on June 26 2000. Since then, the cost of sequencing has fallen by a factor of 14,000.

AFP/The Local (news@thelocal.se)

Your comments about this article

08:21 April 16, 2010 by calebian22
I wonder if the researchers at the Karolinska institute were influenced by listening to Freddie Mercury sing Fat Bottom Girls on their mp3s?
08:26 April 16, 2010 by peropaco
LOL. I guess a large percentage of girls from US, Sweden, UK, new of this risk way before any medical reseach. Supersize is the way to go..
08:39 April 16, 2010 by CarlBlack
And what is the difference in chance of getting breast cancer? 3% or 30%? Why don't the journalists ask such basic question?

And why don't they put here link to the article, especially since it is open access?
14:16 April 16, 2010 by 2394040
You wonder if the medical profession knows what it is talking about. For years we've heard that being overweight increases the possibility of certain diseases, including cancer. Now being too thin does it. Do you ever get the impression that the medical profession is mostly interested in scaring people into seeing doctors more than they really need to?
15:15 April 16, 2010 by sissygirl
There we have it. Just LIVE people and quit worrying about every morsel you consume. All we hear is "This causes cancer, that prevents cancer." My mother was obese. She prayed I would not be fat. I was always a shrimp to her relief. And now I might get cancer. Bring on the cigarrettes and red M&Ms!
15:38 April 16, 2010 by AndreaGerak
"...and throws up new drug targets" - this is the point of this research.

Money talks. Simple.

If you wanna know a bit more about cancer research that fro example Cancerfonden doesn't like to tell us:

http://www.thelocal.se/blogs/stuckinstockholm/2010/04/09/cancer-research-forward-or-backward/
Today's headlines
Perspective: ‘Russian sub’ alert
Why a foreign vessel lurks in Swedish waters
The HMS Stockholm patrols Jungfrufjärden in the Stockholm archipelago on Monday morning. Photo: Anders Wiklund/TT

Why a foreign vessel lurks in Swedish waters

With Sweden engaged in its biggest domestic military operation since the Cold War, The Local spoke to Johan Wiktorin, a fellow at the Swedish Royal Academy of War Sciences, to get insight into what’s going on in the Stockholm archipelago. READ  

Over 20 Swedish flights hit by Lufthansa strike
Grounded Lufthansa planes. Photo: TT

Over 20 Swedish flights hit by Lufthansa strike

A strike by pilots at German airline Lufthansa will affect over 20 flights in and out of Sweden over the next two days. READ  

National
Dentist gives free care to Roma beggars
Photo: Shutterstock

Dentist gives free care to Roma beggars

A dentist in western Sweden is offering free dental care to his town's Roma begging population. READ  

Ebola crisis
Stockholm patient does not have Ebola
Infection clinic at Karolinska University Hospital in Huddinge. Photo: Fredrik Sandberg/TT

Stockholm patient does not have Ebola

UPDATED: A patient at a Stockholm hospital was told on Monday morning that he does not have Ebola, after he was forced to spend the night in isolation. READ  

Business & Money
Electrolux profit soars after cost-cutting efforts
Photo: TT

Electrolux profit soars after cost-cutting efforts

Swedish electrical appliance maker Electrolux reported its third-quarter net profit soared 42 percent to 933 million kronor ($130 million) thanks to a cost-cutting programme started at the end of last year. READ  

National
School photographer fired for homophobic slur
Photo credit: Shutterstock

School photographer fired for homophobic slur

A photographer at a high school in southern Sweden was sacked after he called one of the students a "fag" during a shoot. READ  

Stockholm 'Russian sub' alert
No let-up in search for foreign vessel
Minehunter HMS Koster takes part in the search in the Stockholm archipelago on Sunday. Photo: Marko Säävälä/TT

No let-up in search for foreign vessel

A hunt for foreign underwater activity near Stockholm entered its fourth day on Monday as Sweden’s armed forces vowed to keep searching “day and night” for what media reports suggest may be a damaged Russian vessel. READ  

Ebola crisis
Patient in isolation after airport Ebola alert

Patient in isolation after airport Ebola alert

A male passenger who landed at Stockholm's Arlanda airport has been transferred to an isolation unit amid fears he may be suffering from the Ebola virus. But a specialist was keen to play down concerns. READ  

Stockholm 'Russian sub' alert
Pictured: 'suspicious object' off Swedish coast
Photo: Swedish Armed Forces

Pictured: 'suspicious object' off Swedish coast

Sweden’s Armed Forces have said it is likely a foreign power is conducting operations in Swedish waters, and have released pictures of a suspicious object seen in the Stockholm Archipelago. READ  

Stockholm 'Russian sub' alert
Mystery deepens over reported Russian sub
The HMS Visby combs the Stockholm archipelago on Sunday as the military operation continues. Photo: Marko Säävälä/TT

Mystery deepens over reported Russian sub

Mystery deepened on Sunday over a Swedish military operation triggered by "foreign underwater activity" off the coast of Stockholm, amid an unconfirmed report of a hunt for a damaged Russian submarine. READ  

RECEIVE OUR NEWSLETTER AND ALERTS
National
Sweden deploys troops over underwater threat
Gallery
People-watching: October 19th
TT
Society
QUIZ: How good is your Swedish?
Business & Money
Get your own office in Gothenburg or Stockholm - free for a day
National
A Touch of Scandinavia: Reindeer in the kitchen
Blog updates

19 October

Getting it (Blogweiser) »

"Follow Joel Sherwood on FB Few watch baseball in Sweden. This is excellent when your team loses..." READ »

 

17 October

Editor’s Blog, Oct 17th (The Local Sweden) »

"Hi readers, Here’s the whole week of news in just 60 seconds. The most-read story was about a..." READ »

 
 
 
Lifestyle
What's on in Sweden: October 17th - 24th
Society
The nudity... and nine other things expat men notice in Sweden
Gallery
People-watching: October 15th
Gallery
Your views: Should outdoor smoking be banned in Sweden?
Business & Money
Sweden has 'large hole' in finances
Sponsored Article
Introducing... Finding a job in Stockholm
Society
Monster salmon caught in northern Sweden
Gallery
Property of the week: Lorensberg
National
Scandinavia's child bride
National
Ebola crisis: How is Sweden preparing?
Lifestyle
Sweden's The Bridge to become 'more Danish'
Business & Money
How Sweden is becoming a cashless society
Gallery
Stockholm Burlesque Festival 2014
National
How a little red horse became a symbol for Sweden
Gallery
People-watching: October 12th
Business & Money
The hottest start-ups from southern Sweden
National
What's on in Sweden: October 10th - 17th
National
Stockholm is 'best' region for well-being
Gallery
People-watching: October 8th
National
Five facts to know about Patrick Modiano
Society
My Swedish Career: A French fashionista in Sweden
Society
Swede's anti-bully Facebook tale goes viral
Society
Have you seen Sweden's viral subway cancer campaign?
National
Isis: Swedes linked to Turkish prisoner swap
National
Should Swedes be banned from buying sex abroad?
Gallery
Fredrik Reinfeldt's leaving presents
National
Five Swedish TV shows you shouldn't miss
Gallery
A tool belt, a casserole, and a book. Fredrik Reinfeldt's parliament gifts
TT
Lifestyle
Top five winter festivals in Sweden
TT
National
Sami reindeer herders win mine reprieve
Gallery
Property of the Week: Gamla Enskede
Sponsored Article
How to catch the first lobster of the year
Politics
Ten new minister faces you should know
Tech
First womb transplant baby in world born in Sweden
Gallery
People-watching: October 5th
National
What's on in Sweden
National
Sweden rethinks Afghan translators' protection
Society
Interview with Geena Davis: 'I want to be in a Swedish movie'
Gallery
Stefan Löfven through the years
Gallery
People-watching: October 1st
Team SCA
Sponsored Article
All-female SCA team takes off on Volvo Ocean Race
Latest news from The Local in Austria

More news from Austria at thelocal.at

Latest news from The Local in Switzerland

More news from Switzerland at thelocal.ch

Latest news from The Local in Germany

More news from Germany at thelocal.de

Latest news from The Local in Denmark

More news from Denmark at thelocal.dk

Latest news from The Local in Spain

More news from Spain at thelocal.es

Latest news from The Local in France

More news from France at thelocal.fr

Latest news from The Local in Italy

More news from Italy at thelocal.it

Latest news from The Local in Norway

More news from Norway at thelocal.no

984
jobs available
Swedish Down Town Consulting & Productions
Swedish Down Town Consulting & Productions is an innovative business company which provides valuable assistance with the Swedish Authorities, Swedish language practice and general communications. Call 073-100 47 81 or visit:
www.swedishdowntown.com
PSD Media
PSD Media is marketing company that offers innovative solutions for online retailers. We provide modern solutions that help increase traffic and raise conversion. Visit our site at:
http://psdmedia.se
If you want to drink, that’s your business.
If you want to stop, we can help.

Learn more about English-language Alcoholics Anonymous in Sweden. No dues. No fees. Confidentiality assured.
AA-EUROPE.ORG/SWEDEN