The two were arrested while driving away from the scene of the crime.
“After a period of observation we were able to stop their car and make an undramatic arrest on highway 70 just south of Hedemora,” said Dalarna police spokesman Sven-Åke Petters.
Both are reported to be around 25 years old and resident in the Stockholm area. They have been detained in custody and will be taken in for questioning later in the afternoon.
A secure cash bag was found beside the original getaway vehicle, which was abandoned in Hedemora.
Two younger men, aged 17 and 18, were arrested an hour later.
All four of the suspects have previous convictions for robbery and drug-related offences.
The masked robbers raided the van outside a Lidl supermarket in the central Swedish town.
After the suspects fled from the scene in a red car, police units from Dalarna and the surrounding regions were brought in to aid in the chase.
The vehicle at the centre of the raid belonged to Loomis (formerly Securitas), which recently had its licence to deliver cash revoked by the Stockholm County Administrative Board.
Loomis was told last month that its permit to deliver cash in the capital would be withdrawn on 29th February next year.
Officials said the company’s staff were not properly trained. The failures in the company’s training were “comprehensive, systematic and continuing,” the County Board said in a statement.