The two-time defending champions dominated their visitors from the south in an intense encounter and wrapped up three crucial points thanks to an opportunist strike from Brazilian Lucas Moura and a close-range header from Edinson Cavani.
PSG are now just one point behind Marseille as their unbeaten start to the season, in all competitions, continued in the biggest fixture in French football.
The match in the capital struggled to burst into life despite the return of PSG's Swedish star Zlatan Ibrahimovic who came on with 24 minutes left for his first action since September 21st.
Marseille coach Marcelo Bielsa looked on in shock with the match 1-0 as his side's chances of an equaliser took a severe turn for the worse with 12 minutes left when Giannelli Imbula was shown a straight red card for what appeared to be a minor offence.
Cavani capped a convincing performance for PSG with a poacher's header from just outside the six-yard box with five minutes remaining that capped a perfect week for the capital club who also booked their place in the Champions League knockout phase.
"We played with a lot of intensity and it's a great victory which counts a lot for us," said PSG defender Maxwell.
"Zlatan played well when he came on and he gives us a different dimension. He's a very important player for us so it's good for him that's he's back but we're all looking forward to some rest now," added the 33-year-old Brazilian.
Sweden have named Ibrahimovic in their squad for their next Euro 2016 qualifier against Montenegro on November 15th.
Before the game, Zlatan took to his official Instagram account to dispel any rumours about his injury.
"It feels really good to get out on the pitch again to do what I love. That's all there is to it," he said.
"The injury is in the heel tendon and I've had to work hard on it the last few weeks. Everything else that's been written about the injury is pure fiction. But sure, it might be good reading as some seem to have worse imagination than others."