The snake was spotted by a car driver who saw it "suddenly fall out of the car and on to the road", said Linda Pleyn, a press spokesperson for Skåne's regional police force.
Police officers were called to the scene and took the animal to Malmö Reptile Centre, in Folkets Park, a large green space in Malmö.
"Now it is in good hands and we will see if it is possible to find out who was the owner," Pleyn explained to The Local.
Joakim Bokblad, a snake expert who works at the reptile centre told the TT news agency that the details of what had happened remained slippery.
"I have difficulty seeing how it could have got out of the car [of its own accord]. On the other hand I have difficulty understanding how someone might throw a snake from a car window," he said.
News of the Indian python's discovery comes in the wake of several other snake sightings that have rattled Malmö residents.
Asked what the police made of their sudden increase in reptile-related work, Pleyn responded: "All I can say is yes, we have had a lot to do with snakes. We don't know if it's the same snakes. But we will see what we can find out."