Police were called to the Docentgatan street in the southern Swedish city at around 8.30pm on Tuesday after residents in the area reported hearing the sound of gunshots.
“We found a male person on the ground with gunshot wounds,” police spokesperson Fredrik Bratt told the TT newswire. The man was taken to hospital but died from his injuries.
There were two other shootings in Malmö overnight. Shortly before midnight bullets were fired through a window into a home in the city, without injuring anyone in the apartment. And at five minutes past midnight police were called to the Lindängen district after shots were fired at a bus.
No one was injured and police said there was no known connection to the Fosie shooting.
No suspects have been identified or arrested.
A day ago an 18-year-old woman was seriously injured in another shooting in Malmö. She was found outside together with a man but police believe the shooting took place in an apartment.
The police initially said that the man had been questioned as a witness and was not a suspect. However on Wednesday they revealed he was one of three people being held on suspicion of attempted murder.
“Another person has been detained in absentia,” police spokesperson Nils Norling told TT.
The men held are aged 25-35. Police have released no other information.
According to Skåne University Hospital the woman's condition is serious but stable. Police said there is no known existing threat against her.
Updated at 11.45am to add new information about arrests.