• Sweden edition
 
Caesarean delivery can alter DNA: study

Caesarean delivery can alter DNA: study

Published: 29 Jun 2009 08:07 GMT+02:00
Updated: 29 Jun 2009 08:07 GMT+02:00

The genetic makeup of white blood cells looks different in children delivered via Caesarean compared to that of children born normally, reports Svenska Dagbladet newspaper (SvD).

An explanation for the different DNA sequences might be that those delivered via Caesarean experience greater stress than babies delivered naturally.

While stress builds up gradually during normal birth, the nervous systems of babies delivered via Caesarean are exposed to sudden stress. At the same time, some DNA genes are turned off while others are switched on.

Professor and paediatrician Mikael Norman, one of the researchers involved in the study, explained that stress occurring during vaginal birth is positive and goal-oriented:

“During a Caesarean, the baby is totally unprepared. The stress comes all at once. There are animal experiments that show that negative stress can programme offspring, something that later can play a role in terms of risk of illness.”

The study at Karolinska focused on the white blood cells in the umbilical cords of Caesarean babies and found mutations in their genetic makeup. The researchers noted differences in DNA sequencing of babies delivered via Caesarean and those delivered normally during the first two days after birth.

“We believe it's a pioneering discovery that Caesarean birth can effect genetic makeup up. Previously, the discussions were about the short-term risk for the mother and child,” Norman told SvD.

“This is of an entirely different magnitude and is part of a new way of looking at the side effects of Caesarean birth.”

The Karolinska study is, on one hand, a result of a debate about the health effects of Caesarean delivery and, on the other, a result of the fact that Caesarean as a delivery method has increased from around 5 percent of births in 1973 to 17.5 percent in 2007.

TT/The Local (news@thelocal.se)

Your comments about this article

10:11 June 29, 2009 by Jadarra
This article reads as if they tested only voluntary Caesarean deliveries and the stress was caused from the immediate sensation of birth involved with that.

When I gave birth to my daughter, she experienced the normal 'goal-oriented' stress of trying to come out . . . until her heartbeat stopped and they had to perform an emergency Caesarean delivery. I think whatever caused her heartbeat to stop was a bit more stressful that the shock of suddenly coming into the world.

I wonder if the stress implications they discovered couldln't be related to those types of difficulties in birth, as opposed to the sudden exposure to the outside world.
13:50 June 29, 2009 by karex
This test also reads as if they tested only two groups: natural childbirth vs. C-section.

When I was pregnant, the Dr. told me that EVERYTHING the mother ingests affects the baby. I quit smoking, drinking alcohol and even taking aspirin for headaches. The birth was also anesthetic free.

I woulbe be interested in seeing results of the comparison between three groups: C-section, natural childbirth with anesthetics and natural childbirth without anestethics.

I suspect that the two groups where anesthetics is applied would show a lot more similar results. I question the conclusion of the study. I would be more inclined to believe that the medication was the cause of the effect, and not the stress.

Face it, can you think of greater stress than having to be pushed through a claustrophobic and suffocating passage?
22:26 June 29, 2009 by spy
Yes I can think of greater stress than having to be pushed through a claustrophobic and suffocating passage.

- Being shouted at by your wife whilst waiting for it all happen.
05:57 July 1, 2009 by majorx
Absurd.....unless the doctor could deliver 2 babies with proven identical genes, one by C-section and one by natural birth ....he cant sure the method of delivery was properly isolated in the research as the only possible cause.

He is generating unnecessary fear with a mere observational study and making unfounded far reaching conclusions.
20:04 July 1, 2009 by DayCaptain
In the last 3 generations of my immediate family 6 have asthma and two do not out of 8 born naturally and the only two born by c-section have asthma. If the parent has asthma it is likely to be passed to the offspring. The cancers on my mother's side of the family are all in those born naturally. The only diabetes is type 2 from being overweight.

This is just another stupid, useless study written by somebody looking to publish something, anything, just to get published.
12:22 July 3, 2009 by ameribrit
Ahh, glad to see the N=1 contingent are explaining how the research is wrong again.
14:35 July 6, 2009 by TheObjectiveObserver
Jadarra, the article says the Caesarean's are planned - not emergencies. Since they are not an emergency, there isn't that kind of stress involved.

Karex, Human bodies have been born that way for eons - unlike caesarean which is a relatively new phenomenon for our biology to come to terms with. Try learning about the amazing process of birth and you will see how all the different hormones that are released through labour are very important to the baby. Something they miss out on during a planned caesarean.

Marjorx, If they conducted this study over many babies, there shouldn't be a significant difference between a natural born baby to a planned caesarean baby. And yet there was. The reason why that is the case may not be their explanation, but it really is worthy of further attention.
Today's headlines
American sales squeeze Ericsson profits
Ericsson CEO Hans Vestberg presents the third-quarter earnings report at the company's headquarters in Kista. Photo: Janerik Henriksson/TT

American sales squeeze Ericsson profits

Swedish telecoms equipment maker Ericsson reported a decline in net profit in the third quarter despite an increase in sales, boosted by business in emerging markets. READ  

Stockholm 'sub hunt'
Sweden calls off suspect submarine search
Ships are returning to shore in Sweden. Photo: TT

Sweden calls off suspect submarine search

The core search for a suspected foreign vessel in Swedish waters has been called off. The armed forces said they remained convinced foreign underwater activity had taken place but had not identified an intruder. READ  

Business & Money
US and Japan fuel surge for Volvo trucks
Ed Carbaugh prepares to install parts on a truck engine on an assembly line at Volvo Trucks' powertrain manufacturing facility in Hagerstown, Maryland, March 2014. Photo: Patrick Semansky/AP

US and Japan fuel surge for Volvo trucks

Sweden's Volvo, the world's second-largest maker of trucks, said Friday it saw a spike in profits in the third quarter, boosted by thriving sales in the US and Japanese markets. READ  

Inspectors attacked at rogue doc’s surgery
Cigarettes and beer photo: Shutterstock

Inspectors attacked at rogue doc’s surgery

Inspectors who were sent to shut down a doctor’s surgery in Gothenburg were physically attacked and fled the premises to get help from the police. READ  

Interview
'Too many concerts feel the same'
Sofar hosts secret gigs in Swedish apartments. Photo: Sofar

'Too many concerts feel the same'

Kattis Bjork founded Stockholm's secret gig scene - Sofar - a year ago. The Local caught up with her as she prepared to celebrate the project's anniversary this weekend and revealed the concept will spread to other Swedish cities in 2015. READ  

Police turn Swede’s vodka into water
A Swede loads a car with alcohol in northern Germany. File photo: Drago Prvulovic/TT

Police turn Swede’s vodka into water

Swedish police say they will pay a man 16,000 kronor ($2,200) in damages after much of the alcohol they confiscated from him was stolen, while many of the bottles they returned were filled with water. READ  

Diplomacy
US to get first female ambassador in Sweden
File photo: Athena Center for Leadership Studies

US to get first female ambassador in Sweden

The United States Embassy in Stockholm is set to get its first female ambassador after the White House announced it was nominating the Iranian-American ex-investment banker Azita Raji to take over from Mark Brzezinski. READ  

Neo-Nazi attacks
Neo-Nazis cleared of knife attack on Nigerian
Police intervene after neo-Nazis attack an anti-Nazi rally in Kärrtorp, December 2013. Photo: Hampus Andersson/TT

Neo-Nazis cleared of knife attack on Nigerian

A Stockholm court has cleared three neo-Nazis of stabbing a Nigerian man in an unprovoked attack. But two of the men will face jail after they were convicted of racial agitation at a riot. READ  

Julian Assange
Assange court ruling expected on Monday
Julian Assange at Ecuador's embassy in the UK. Photo: Anthony Devlin

Assange court ruling expected on Monday

WikiLeaks founder Julian Assange can expect the next court ruling on his case to take place on Monday October 27th in Stockholm. READ  

Politics
Sweden to get EU 'Christmas present'
Sweden's Prime Minister Stefan Löfven at an EU summit in Brussels this week. Photo: TT

Sweden to get EU 'Christmas present'

Sweden is set to get 1.2 billion kronor ($168 million) back from the EU on December 1st, according to leaked EU documents which suggest that other European countries will have to make large top-up payments this year. READ  

RECEIVE OUR NEWSLETTER AND ALERTS
Lifestyle
What's On in Sweden: October 24th - 31st
Gallery
People-watching: October 22nd
Gallery
In Pictures: Prince Carl Philip and Sofia Hellqvist
Lifestyle
Eight things to love about renting a Swedish apartment
National
Vasa ship cannon blasted in Sweden
Blog updates

24 October

Editor’s blog, October 24th (The Local Sweden) »

"Hi readers, Get ready to read our weekly digest of Swedish news in less than 60 seconds. The..." READ »

 

24 October

Is darkness weather? (Blogweiser) »

"I try very hard not to talk about the weather. This has come after a decade..." READ »

 
 
 
National
Sub hunt: Day-by-day
National
Sub hunt: Stockholm islanders share their fears with The Local
Sponsored Article
The best options for oversea transfers
National
Get 20% off unique Swedish homeware
National
Dentist gives free care to Roma beggars
Business & Money
Get your own office in Gothenburg or Stockholm - free for a day
Gallery
Property of the week: Malmö
Gallery
PHOTOS: 'Foreign activity' in Swedish waters
Gallery
People-watching: October 19th
TT
Society
QUIZ: How good is your Swedish?
Lifestyle
What's on in Sweden: October 17th - 24th
Society
The nudity... and nine other things expat men notice in Sweden
Gallery
People-watching: October 15th
Gallery
Your views: Should outdoor smoking be banned in Sweden?
Business & Money
Sweden has 'large hole' in finances
Sponsored Article
Introducing... Finding a job in Stockholm
Society
Monster salmon caught in northern Sweden
Gallery
Property of the week: Lorensberg
National
Scandinavia's child bride
National
Ebola crisis: How is Sweden preparing?
Business & Money
How Sweden is becoming a cashless society
Gallery
Stockholm Burlesque Festival 2014
National
How a little red horse became a symbol for Sweden
Gallery
People-watching: October 12th
Business & Money
The hottest start-ups from southern Sweden
National
What's on in Sweden: October 10th - 17th
National
Stockholm is 'best' region for well-being
Gallery
People-watching: October 8th
National
Five facts to know about Patrick Modiano
Society
My Swedish Career: A French fashionista in Sweden
Society
Swede's anti-bully Facebook tale goes viral
Society
Have you seen Sweden's viral subway cancer campaign?
National
Isis: Swedes linked to Turkish prisoner swap
National
Should Swedes be banned from buying sex abroad?
Gallery
Fredrik Reinfeldt's leaving presents
National
Five Swedish TV shows you shouldn't miss
Gallery
A tool belt, a casserole, and a book. Fredrik Reinfeldt's parliament gifts
TT
Lifestyle
Top five winter festivals in Sweden
TT
National
Sami reindeer herders win mine reprieve
Gallery
Property of the Week: Gamla Enskede
Sponsored Article
How to catch the first lobster of the year
Team SCA
Sponsored Article
All-female SCA team takes off on Volvo Ocean Race
Latest news from The Local in Austria

More news from Austria at thelocal.at

Latest news from The Local in Switzerland

More news from Switzerland at thelocal.ch

Latest news from The Local in Germany

More news from Germany at thelocal.de

Latest news from The Local in Denmark

More news from Denmark at thelocal.dk

Latest news from The Local in Spain

More news from Spain at thelocal.es

Latest news from The Local in France

More news from France at thelocal.fr

Latest news from The Local in Italy

More news from Italy at thelocal.it

Latest news from The Local in Norway

More news from Norway at thelocal.no

979
jobs available
Swedish Down Town Consulting & Productions
Swedish Down Town Consulting & Productions is an innovative business company which provides valuable assistance with the Swedish Authorities, Swedish language practice and general communications. Call 073-100 47 81 or visit:
www.swedishdowntown.com
PSD Media
PSD Media is marketing company that offers innovative solutions for online retailers. We provide modern solutions that help increase traffic and raise conversion. Visit our site at:
http://psdmedia.se
If you want to drink, that’s your business.
If you want to stop, we can help.

Learn more about English-language Alcoholics Anonymous in Sweden. No dues. No fees. Confidentiality assured.
AA-EUROPE.ORG/SWEDEN