• Sweden edition
 
2011 NOBEL PRIZES
Three share 2011 Nobel in medicine

Three share 2011 Nobel in medicine

Published: 03 Oct 2011 11:21 GMT+02:00
Updated: 03 Oct 2011 11:21 GMT+02:00

Three researchers have been jointly awarded the 2011 Nobel Prize in Physiology or Medicine for discoveries related to the immune system.

The prize was divided, with one half going jointly to Bruce A. Beutler and Jules A. Hoffmann "for their discoveries concerning the activation of innate immunity" and the other half to the late Ralph M. Steinman "for his discovery of the dendritic cell and its role in adaptive immunity".

The three scientists together have “revolutionized our understanding of the immune system”, according to a statement from The Nobel Assembly at Karolinska Institutet through research unlocking secrets about how people's bodies fight off diseases.

Beutler, an American currently at the Scripps Research Institute in California and Jules Hoffmann, a Luxembourg-born scientist who spent most of his career in France, discovered receptor proteins that can recognize such microorganisms and activate innate immunity, the first step in the body's immune response.

Meanwhile, Steinman a Canadian affiliated with Rockefeller University in New York, discovered the dendritic cells of the immune system and their unique capacity to activate and regulate adaptive immunity, the later stage of the immune response during which microorganisms are cleared from the body.

Steinman died last weekend of cancer, according to a report in the Canadian press, with the news only reaching the Nobel Committee after the award had been announced.

While much about the immune system has been learned over the course of the 20th century, prior to the work of the three scientists, the mechanisms triggering the activation of innate immunity and mediating the communication between innate and adaptive immunity remained a mystery.

Together, the discoveries "provided novel insights into the activation and regulation of our immune system", according to the Nobel Committee.

"They have made possible the development of new methods for preventing and treating disease, for instance with improved vaccines against infections and in attempts to stimulate the immune system to attack tumors."

In addition, the discoveries have increased understanding as to why the immune system can "attack our own tissues", information which offers clues for new treatments of inflammatory diseases.

The Local/dl (news@thelocal.se)

Don't miss...X
Left Right

Your comments about this article

15:00 October 3, 2011 by jacquelinee
Hurray for Luxembourg, The USA and Canada! Hopefully the work of these great reearchers will help in finding a cure for immune related diseases such as Aids.
00:17 October 4, 2011 by wolfbay
I'm glad the Nobels are not awarded in America. There would be great pressure for" affirmative action" based on gender and race. Two out of the three were Jews- those pesky trouble makers.Impressive the Swedes awarded it to them. Malmo must have no input.
02:01 October 4, 2011 by shahislam
Infoseeker: for your honour.

Violent means are ugly!

The top leaders sometimes have no choice but to act foolish or real mean to please some and survive and then, try to balance things! There is no alternative in the system of capitalism where money (not morality) operates the main switch of power. But the good news is: sense of morality works perfectly on smaller powers; this happens through the silent balancing acts of cosmic rules, I sometime talk about.

I commented in the Washington Post today as follows:

Even if any of the terrorist-US-citizens was captured, he (al-Awlaki) /she wouldn't be receiving anything less than suspended death penalty. However, as an only option, killing of a proved killer for belief-blind or what so ever reasons is unavoidable!

It will be a wastage of time to argue on what is justified by common sense!

Moreover, for the religious guys there is nothing for them to argue about because crusading-minded guys killed in wars, straight head for paradisaical-life after death; so, being killed is a blessing to those who want to live in heaven after death!

About Ivory Coast: This Gbagbo, if option of amnesty was honestly given by impartial UN, would not surrender willingly, therefore, should receive suspended death penalty. There are many mentally retarded stupids in 'Tiger-like powers' in many countries and a newer UN can only help replace these idiots in slow evolutionary -type revolutions.

(Suspended death sentences for inhuman war crime-committing world-leaders mean when found guilty they have serve in the UN's front line of fights against insurgents and slow implementation of such noble ideas is possible by human push too.)

Same will be the situation about Gaddafi and many others to be followed later, if slow transition may continue undisturbed.

I am sure, many cannot even guess where Obama's success is coming from, in the midst of similar conditions where Bushes failed!

God bless us all and we continue to be less worried and more happy!
06:24 October 5, 2011 by mkvgtired
@shahislam, Way off topic. This is about an award going to people researching how to save lives.

It is very sad that one of the researchers died one week before getting this award. This would have probably been one of his proudest moments. A Nobel prize for science is a HUGE deal. Truly sad, but I am sure it will help his grieving family realize how much he changed this world for the better. Oddly enough, fighting the same disease that killed him.

Good luck to the remaining researchers in their work.
Today's headlines
Dismemberment killer gets sentence cut
The search and rescue operation in northern Sweden. File photo: TT

Dismemberment killer gets sentence cut

The 22-year-old man convicted of murdering his ex-girlfriend in northern Sweden had his sentence reduced on Wednesday, in part due to his "peculiar personality". READ () »

School gas leak sends 25 to hospital

School gas leak sends 25 to hospital

An elementary school in southern Sweden was evacuated on Wednesday and dozens of pupils were taken to hospital after the smell of gas spread through the rooms. READ () »

Swedes vote for country's nicest cock
The Flymen Church weathercock in all its newly gilded glory. Photo: TT

Swedes vote for country's nicest cock

A Swedish churchwarden has reacted with joy upon finding out the parish has Sweden's nicest weathercock. READ () »

Greens push rich tax to finance schools
Per Bolund of The Greens. File photo: TT

Greens push rich tax to finance schools

Sweden's third largest party The Greens revealed its shadow budget on Wednesday, targeting schools and youth employment. High earners would have to pitch in more. READ () »

Holiday status updates 'not a burglary risk'
Ibiza, you say? File photo: Jonas Ekströmer/TT

Holiday status updates 'not a burglary risk'

Mythbusting Swedish researchers have found no link between gushing about your upcoming holiday online and returning to an emptied house. They told The Local that a trip to Ikea could be much more dangerous. READ () »

Woman charged after accusing beggar of theft
The people in this picture are not those from the story. Photo: TT

Woman charged after accusing beggar of theft

A woman in Gothenburg who accused a beggar of robbing her has been charged with fraud and false accusations. READ () »

Swedish royals set baptism date for princess
Photo: Kungahuset

Swedish royals set baptism date for princess

Sweden's royal family has set the date for the baptism of Princess Leonore. READ () »

The Local List
Evidence Game of Thrones is set in Sweden

Evidence Game of Thrones is set in Sweden

With Swedish Game of Thrones fans frothing at the mouth at the season four premiere, The Local revisits its list of ten reasons why the hit books and show are (probably) based in Sweden. READ () »

'Baffling' Swedish raid on German sub makers
The Kockums Malmö shipyard and FMV headquarters. Files: TT

'Baffling' Swedish raid on German sub makers

After the Swedish military raided the Malmö premises of German defence giant Thyssen Krupp, a military expert tells The Local why recent Russian aggression means Sweden's Saab needs to take control of national submarine production. READ () »

Swedish kids crack adult content 'code' at school
A child, unrelated to the story, on her computer. File photo: TT

Swedish kids crack adult content 'code' at school

Swedish parents who busted their children looking at adult content online were shocked to find the kids saying 'they'd learned the code at school'. READ () »

RECEIVE OUR NEWSLETTER AND ALERTS
Politics
Who's the prime minister's heir?
Alfie Atkins
Society
Are children's books the key to families integrating in Sweden?
National
'Sweden Dem protests cater to party's martyr image'
National
'Swedish research grants were fantastic, but now it's like Australia'
Society
Only in Sweden: The ten problems you'd never encounter elsewhere
National
Swedes stopped to take my picture, but didn't look me in the eyes
Business & Money
A swipe of the hand replaced cash and cards in Lund
YouTube
Features
Video: Oliver Gee finds out how to embrace The Swedish Hug
TT
National
Abba duo hints at reunion
Private
National
Flash mobs hug it out across Sweden
Finest.se
Gallery
People-watching April 11-13
TT
Politics
Swedes to give six-hour workday a go
Advertisement:
TT
Society
Aussie choir member wows Abba in Sweden
YouTube
Society
Stockholm magic a surprise YouTube hit
Fastighetsbyrån
Society
Gallery: The Local's Property of the Week
Private
Society
Swedes find 200-year-old gravestone in living room
Stockholm School of Economics
Sponsored Article
Why a bachelor's degree is no longer enough
Deepti Vashisht
Features
Deepti Vashisht dissects the magic of Sweden's personal ID number
Shutterstock
Society
Ten signs you've been in Sweden too long
Society
Jimi Fritze heard every word when doctors discussed taking his organs
Society
A Swedish farmer explains why the new bestiality ban is 'pointless'
Society
'Blondes have more brains': Swedish study
TT
Society
VIDEO: Leaked 'Save Slussen' film goes viral
finest.se
Gallery
People-watching, March 28-30
ESL
Sponsored Article
Learning Swedish the easy way
Latest news from The Local in Switzerland

More news from Switzerland at thelocal.ch

Latest news from The Local in Germany

More news from Germany at thelocal.de

Latest news from The Local in Spain

More news from Spain at thelocal.es

Latest news from The Local in France

More news from France at thelocal.fr

Latest news from The Local in Italy

More news from Italy at thelocal.it

Latest news from The Local in Norway

More news from Norway at thelocal.no

Blog Update: The Diplomatic Dispatch

28 October 15:16

The Green Growth Group Summit »

"Today on the 28 October in Brussels, a large group of key EU Ministers and business people, including UK Secretary of State for Energy and Climate Change Edward Davey, and Swedish Environment Minister Lena Ek, will meet to discuss green growth. They all have a stake in resolving a challenge which, although it is crucial..." READ »

737
jobs available
Swedish Down Town Consulting & Productions
Swedish Down Town Consulting & Productions is an innovative business company which provides valuable assistance with the Swedish Authorities, Swedish language practice and general communications. Call 073-100 47 81 or visit:
www.swedishdowntown.com