• Sweden edition
 
2011 NOBEL PRIZES
Three share 2011 Nobel in medicine

Three share 2011 Nobel in medicine

Published: 03 Oct 2011 11:21 GMT+02:00
Updated: 03 Oct 2011 11:21 GMT+02:00

The prize was divided, with one half going jointly to Bruce A. Beutler and Jules A. Hoffmann "for their discoveries concerning the activation of innate immunity" and the other half to the late Ralph M. Steinman "for his discovery of the dendritic cell and its role in adaptive immunity".

The three scientists together have “revolutionized our understanding of the immune system”, according to a statement from The Nobel Assembly at Karolinska Institutet through research unlocking secrets about how people's bodies fight off diseases.

Beutler, an American currently at the Scripps Research Institute in California and Jules Hoffmann, a Luxembourg-born scientist who spent most of his career in France, discovered receptor proteins that can recognize such microorganisms and activate innate immunity, the first step in the body's immune response.

Meanwhile, Steinman a Canadian affiliated with Rockefeller University in New York, discovered the dendritic cells of the immune system and their unique capacity to activate and regulate adaptive immunity, the later stage of the immune response during which microorganisms are cleared from the body.

Steinman died last weekend of cancer, according to a report in the Canadian press, with the news only reaching the Nobel Committee after the award had been announced.

While much about the immune system has been learned over the course of the 20th century, prior to the work of the three scientists, the mechanisms triggering the activation of innate immunity and mediating the communication between innate and adaptive immunity remained a mystery.

Together, the discoveries "provided novel insights into the activation and regulation of our immune system", according to the Nobel Committee.

"They have made possible the development of new methods for preventing and treating disease, for instance with improved vaccines against infections and in attempts to stimulate the immune system to attack tumors."

In addition, the discoveries have increased understanding as to why the immune system can "attack our own tissues", information which offers clues for new treatments of inflammatory diseases.

The Local/dl (news@thelocal.se)

Your comments about this article

15:00 October 3, 2011 by jacquelinee
Hurray for Luxembourg, The USA and Canada! Hopefully the work of these great reearchers will help in finding a cure for immune related diseases such as Aids.
00:17 October 4, 2011 by wolfbay
I'm glad the Nobels are not awarded in America. There would be great pressure for" affirmative action" based on gender and race. Two out of the three were Jews- those pesky trouble makers.Impressive the Swedes awarded it to them. Malmo must have no input.
02:01 October 4, 2011 by shahislam
Infoseeker: for your honour.

Violent means are ugly!

The top leaders sometimes have no choice but to act foolish or real mean to please some and survive and then, try to balance things! There is no alternative in the system of capitalism where money (not morality) operates the main switch of power. But the good news is: sense of morality works perfectly on smaller powers; this happens through the silent balancing acts of cosmic rules, I sometime talk about.

I commented in the Washington Post today as follows:

Even if any of the terrorist-US-citizens was captured, he (al-Awlaki) /she wouldn't be receiving anything less than suspended death penalty. However, as an only option, killing of a proved killer for belief-blind or what so ever reasons is unavoidable!

It will be a wastage of time to argue on what is justified by common sense!

Moreover, for the religious guys there is nothing for them to argue about because crusading-minded guys killed in wars, straight head for paradisaical-life after death; so, being killed is a blessing to those who want to live in heaven after death!

About Ivory Coast: This Gbagbo, if option of amnesty was honestly given by impartial UN, would not surrender willingly, therefore, should receive suspended death penalty. There are many mentally retarded stupids in 'Tiger-like powers' in many countries and a newer UN can only help replace these idiots in slow evolutionary -type revolutions.

(Suspended death sentences for inhuman war crime-committing world-leaders mean when found guilty they have serve in the UN's front line of fights against insurgents and slow implementation of such noble ideas is possible by human push too.)

Same will be the situation about Gaddafi and many others to be followed later, if slow transition may continue undisturbed.

I am sure, many cannot even guess where Obama's success is coming from, in the midst of similar conditions where Bushes failed!

God bless us all and we continue to be less worried and more happy!
06:24 October 5, 2011 by mkvgtired
@shahislam, Way off topic. This is about an award going to people researching how to save lives.

It is very sad that one of the researchers died one week before getting this award. This would have probably been one of his proudest moments. A Nobel prize for science is a HUGE deal. Truly sad, but I am sure it will help his grieving family realize how much he changed this world for the better. Oddly enough, fighting the same disease that killed him.

Good luck to the remaining researchers in their work.
Today's headlines
Politics
Nuclear freeze agreed by new government
A nuclear power station in Forsmark, Sweden. Photo: TT

Nuclear freeze agreed by new government

Sweden's Social Democrats and Greens Party have announced a coalition agreement to halt nuclear energy development. READ  

International
Sweden rethinks Afghan translators' asylum
A Swedish soldier in Afghanistan. Photo: TT

Sweden rethinks Afghan translators' asylum

The Migration Court in Malmö has ruled that Sweden's Migration Board was wrong to reject the residence applications of seven Afghan interpreters without assessing their protection needs. READ  

The Local List
Top five winter festivals in Sweden
Speak Percussion will perform at Connect in Malmö in November. Photo: Connect

Top five winter festivals in Sweden

Autumn has swept into the country and chilly days lie ahead. But there are plenty of winter festivals where you can warm up in the coming months. With tickets already selling fast, here are The Local's top tips. READ  

Business
Swedish Saab plant sheds a third of workers
Workers at the Saab plant in Trollhättan. Photo: TT

Swedish Saab plant sheds a third of workers

Swedish car maker Saab has announced it has axed 155 workers, close to a third of its workforce. READ  

International
Sweden's 'most dangerous art' on sale
A Danish site is selling the works that the Swedish state wants destroyed. Screenshot: www.entartetekunst.dk

Sweden's 'most dangerous art' on sale

Work by controversial jailed Swedish artist Dan Park is on sale online and could reach a gallery in Copenhagen, despite a previous exhibition being pulled. READ  

Society
Sweden is 'second best' place to grow old
Pensioners in Sweden. Photo: TT

Sweden is 'second best' place to grow old

Sweden has dropped to second place in an annual index measuring the quality of life of elderly people in 96 countries around the world. READ  

National
Top Swedish skier killed in Chile avalanche
Andreas Fransson, left. Photo: Markus Alatalo

Top Swedish skier killed in Chile avalanche

UPDATED: The bodies of two of the world's top skiers, Sweden's Andreas Fransson and JP Auclair from Canada, were found on Tuesday after they were reported missing in an avalanche in the Andes. READ  

Politics
Coalition promise to boost welfare and jobs
Social Democrat leader Stefan Löfven. Photo: TT

Coalition promise to boost welfare and jobs

UPDATED: The Social Democrats and the Greens have agreed to raise unemployment payments and promised to create more jobs in the construction industry, The Local has learned. READ  

National
Ikea recalls elk pasta
Two types of pasta are affected. Photo: IKEA

Ikea recalls elk pasta

Ikea has pulled two different types of elk-shaped pasta from its stores in Sweden. READ  

Presented by Regus
How to get your own great office in Stockholm
A woman using a Regus workspace. Photo: Regus

How to get your own great office in Stockholm

Stockholm's business climate is hotter than ever, which leaves start-ups and business travellers hunting high and low for flexible office space. The solution is easier than they think. READ  

RECEIVE OUR NEWSLETTER AND ALERTS
National
Apology for Swedish model's stolen photos
Politics
New coalition agrees on defence and migration
Fastighetsbyrån
Gallery
Property of the week: Botkyrka
Education
New government to make school compulsory to 18
Politics
Sweden Democrat wins Deputy Speaker spot
Blog updates

28 September

Spoiled Doyle (Blogweiser) »

"What you gotta watch out for in Sweden is the good stuff. http://www.youtube.com/watch?v=Re_EzUe6xpI In Sweden, it’s the good things you have to watch out for. Video on @TheLocalSweden http://t.co/rAb8eGFdTD pic.twitter.com/w37YYwMXy1 — Joel Sherwood (@joeldsherwood) September 29, 2014 " READ »

 

26 September

 (The Local Sweden) »

"Hi readers, Autumn swept into Sweden at the start of this week with snow in the north of the country and flooding in the south. As well as a change in the weather, Sweden’s change in political direction became clearer, with Social Democrat leader Stefan Lofven formally announcing his party would work with the Greens as..." READ »

 
 
 
National
Swedish scientists sneak Bob Dylan lyrics into articles
Lifestyle
The five best Swedish songs of the month
Gallery
People-watching: September 28th
National
When Italian style meets Swedish simplicity
Lifestyle
Review: Sweden's first alcohol-free nightclub
Gallery
In Pictures: The MS Estonia disaster
Lifestyle
Ten things expat women notice in Sweden
Politics
What's next on Sweden's political stage?
Gallery
Sweden's 2014 election: Most memorable moments
Society
What's on in Sweden
Gallery
People-watching: September 24th
Seaman Oliver Gee with his first lobster
Lifestyle
How to catch the first lobster of the year
Gallery
In Pictures: Fredrik Reinfeldt through the years.
Society
Plucked out of Canada for love and guitars
Politics
How Sweden Democrats went mainstream
Politics
Scandinavia and Scotland: closer links?
Sponsored Article
How to start a business in Stockholm
Society
Why is Stockholm's Södermalm so cool?
Politics
Sweden elections: Who's who?
Sponsored Article
Introducing… Insurance in Stockholm
Latest news from The Local in Austria

More news from Austria at thelocal.at

Latest news from The Local in Switzerland

More news from Switzerland at thelocal.ch

Latest news from The Local in Germany

More news from Germany at thelocal.de

Latest news from The Local in Denmark

More news from Denmark at thelocal.dk

Latest news from The Local in Spain

More news from Spain at thelocal.es

Latest news from The Local in France

More news from France at thelocal.fr

Latest news from The Local in Italy

More news from Italy at thelocal.it

Latest news from The Local in Norway

More news from Norway at thelocal.no

866
jobs available
Swedish Down Town Consulting & Productions
Swedish Down Town Consulting & Productions is an innovative business company which provides valuable assistance with the Swedish Authorities, Swedish language practice and general communications. Call 073-100 47 81 or visit:
www.swedishdowntown.com
PSD Media
PSD Media is marketing company that offers innovative solutions for online retailers. We provide modern solutions that help increase traffic and raise conversion. Visit our site at:
http://psdmedia.se
If you want to drink, that’s your business.
If you want to stop, we can help.

Learn more about English-language Alcoholics Anonymous in Sweden. No dues. No fees. Confidentiality assured.
AA-EUROPE.ORG/SWEDEN