• Sweden's news in English

Swedish researchers in 'depression gene' find

Peter Vinthagen Simpson · 28 Sep 2011, 15:01

Published: 28 Sep 2011 15:01 GMT+02:00

Facebook Twitter Google+ reddit

Previous studies have shown that bipolar disorder, previously known as manic depression and afflicting around one percent of adults worldwide, is to a great extent dependent on inherited factors.

It has hitherto been unknown just which genes play a role and thus little is known about the mechanisms that shape the debilitating illness.

The study which involved 50,000 people and researchers from Sweden, Europe and the US, has now identified a specific gene which they believe has a particularly strong connection to the often baffling condition.

"The gene, called CACNA1C, codes for calcium channel in the brain. It is interesting as certain medicines to combat bipolar syndrome affect just this channel," said Michael Landén, the Sahlgrenska Academy researcher leading the Gothenburg University team in the international study.

It is hoped that the identification of the gene, which has also been previously associated with schizophrenia, will encourage further research on how the calcium pathway affects the brain.

Story continues below…

"The fact is that it will be necessary to develop a broader base of material if we are going to learn about bipolar syndrome, and there Sweden can make a valuable contribution," Landén said.

The study was published last Sunday in the prestigious medical journal Nature Genetics.

Peter Vinthagen Simpson (news@thelocal.se)

Facebook Twitter Google+ reddit

Your comments about this article

16:01 September 28, 2011 by StockholmSam
"Swedish researchers at Sahlgrenska Academy at the University of Gothenburg have managed to identify a gene connected which they believe have a strong connection to bipolar disorder."

I'm sorry, but what the h*ll kind of English was THAT?
16:53 September 28, 2011 by neoz717
I think would sound better as:

Swedish researchers at Sahlgrenska Academy from the University of Gothenburg have managed to identify a gene which they believe is linked to bipolar disorder.
19:55 September 28, 2011 by StockholmSam
Yep. Too bad The Local can't hire decent proofreaders.
21:49 September 28, 2011 by Kstock
The great Norwegian explorer Roald Amundsen was bipolar.
09:29 September 29, 2011 by Pont-y-garreg
I think there is a defective gene at TheLocal that is responsible for poor English and frequent grammatical errors.
10:43 September 29, 2011 by Byggare Bob
Go easy on them, resources are no doubt stretched and mistakes occasionally get made. Dagens Industri called Madeleine the "Crown Princess" in a headline yesterday - to err is human.

Interesting story. Seems Swedish researchers are very often involved in these international studies of note.
23:04 September 30, 2011 by D. ane
It is interesting that the gene is involved with calcium chanels. Calcium is often regarded as the calming mineral and can have a sedative effect on manic / depressive behaviour.

I have also read that microwaves as emitted from mobile phones can affect calcium chanels in the brain and some people believe that microwaves can make people depressed.

May be one day we will understand the connection between all these!
Today's headlines
Facebook slammed for cutting Swedish breast cancer video
File photo of the landing page of the Swedish version of Facebook. Photo: Christine Olsson/TT

The social media giant removed a breast cancer awareness video because it deemed the images "offensive," according to the Swedish Cancer Society.

Pastor rapped for depicting rival as Nazi in church play
A different pastor. Photo: Christine Olsson/TT

The pastor allegedly found it funny.

In Pictures: Look inside this perfect Swedish island home
This modern Gotland home was designed and built by two Swedes. Photo: United Frog Studios/AB

Anna-Lena and Johan designed and built their home with tall beautiful windows, a smart heating system, and a separate section for their greyhounds.

Cannabis worth millions seized at Swedish port
A file photo of a Swedish police cannabis find not related to the story. Photo: Polisen

The 300kg haul was found by in a truck which drove off a ferry in Karlskrona.

Roll over Volvo: there’s a new Swedish car in town
Photo: Björn Olsson

Car developers in Gothenburg have given Volvo a new sibling.

Thaw trip: Swedish PM Löfven heads to Saudi Arabia
Margot Wallström was at the centre of the 2015 diplomatic crisis. She will not join the Prime Minister on his trip to Saudi Arabia. Photo: Adam Ihse/TT

There are fences that need mending.

Here's where it could snow in central Sweden this weekend
This shot of snow in western Sweden may not be as far away as you think. Photo: Johan Eklund/TT

...and it's still only October.

Fury at plans that 'threaten the IB's survival' in Sweden
The new rules are unfair, say Swedish IB pupils. Photo: Berit Roald/NTB scanpix/TT

A new system for converting the grades of International Baccalaureate students in Sweden will make it almost impossible for them to get into top Swedish universities, it has been claimed.

Education doesn’t always pay in Sweden: study
Nurses are paid less than a lot of non-college graduates. Photo: Bertil Ericsson/TT

Half of Swedish graduates would earn more in their lifetime if they instead started work straight after high school, a new study shows.

What's On in Sweden
Five ways to discover something new in Sweden this weekend
Frank Zappa's symphonic works will be performed in Malmö this weekend. Photo: Anonymous/AP

From a performance of Frank Zappa's unheralded orchestral work to an intriguing combination of circus and opera, Sweden has some unique events this weekend.

Sponsored Article
This is Malmö: Football capital of Sweden
Analysis & Opinion
Are we just going to let half the country die?
Sponsored Article
Where is the Swedish music industry heading?
Angry elk chases Swede up a lamp post
The Local Voices
'Alienation in Sweden feels better: I find myself a stranger among scores of aliens'
Blog updates

8 July

Editor’s blog, July 8th (The Local Sweden) »

"Hej readers, It has, as always, been a bizarre, serious and hilarious week in Sweden. You…" READ »


6 October

10 useful hjälpverb (The Swedish Teacher) »

"Hej! I think the so-called “hjalpverb” (auxiliary verbs in English) are a good way to get…" READ »

Sponsored Article
7 reasons you should join Sweden's 'a-kassa'
People-watching: October 20th
Sponsored Article
Why you should 'grab a chair' on Stockholm's tech scene
The Local Voices
A layover at Qatar airport brought this Swedish-Kenyan couple together - now they're heading for marriage
Swede punches clown that scared his grandmother
Fans throw flares and enter pitch in Swedish football riot
Sponsored Article
Stockholm: creating solutions to global challenges
Could Swedish blood test solve 'Making a Murderer'?
Sponsored Article
Swedish for programmers: 'It changed my life'
Property of the week: Linnéstaden, Gothenburg
Swedish school to build gender neutral changing room
Sponsored Article
Top 7 tips to help you learn Swedish
People-watching: October 14th-16th
Sponsored Article
How to vote absentee from abroad in the US elections
Man in Sweden assaulted by clowns with broken bottle
Nobel Prize 2016: Literature
Sponsored Article
'There was no future for me in Turkey'
Watch the man who discovered Bob Dylan react to his Nobel Prize win
Sponsored Article
‘Extremism can't be defeated on the battlefield alone’
Record numbers emigrating from Sweden
Sponsored Article
Stockholm: creating solutions to global challenges
People-watching: October 12th
Sponsored Article
Why you should 'grab a chair' on Stockholm's tech scene
The Local Voices
'Swedish startups should embrace newcomers' talents - there's nothing to fear'
Sponsored Article
'There was no future for me in Turkey'
How far right are the Sweden Democrats?
Sponsored Article
Where is the Swedish music industry heading?
Property of the week: Triangeln, Malmö
Sponsored Article
Last chance to vote absentee in the US elections
Sweden unveils Europe's first elk hut
People-watching: October 7th-9th
The Local Voices
Syria's White Helmets: The Nobel Peace Prize would have meant a lot, but pulling a child from rubble is the greatest reward
Missing rune stone turns up in Sweden
Nobel Prize 2016: Chemistry
People-watching: October 5th
Must-watch: Incredible time-lapse video of Northern Lights in Sweden
The Local Voices
Why this Russian developer is committed to helping refugees - with tech
jobs available